Research Interests:
Our lab focuses on the molecular mechanisms underlying the fetal sex-specific dysregulation of fetal endothelial function (such as disturbed angiogenesis and responses to TNF-α) in complicated pregnancies, and the maternal obesity-associated fetal endothelial dysfunction and future health risks of the offspring. Our research utilizing multiple model systems including human placenta tissue, human cell models, and in vivo animal models. Results from our research will provide new insights into discovering novel biomarkers or therapeutic targets for sex-specific endothelial dysregulation in children born to complicated pregnancies.