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Popi Siziopikou, MD, PhD

Professor and Vice Chair for Research
Director of The Ginny L. Clements Breast Cancer Institute
The Ginny L. Clements Breast Cancer Clinical Endowed Chair
University of Arizona Comprehensive Cancer Center

Dr. Siziopikou serves as Professor and Vice Chair of Pathology for Research at the Department of Pathology and Laboratory Medicine at the University of Arizona. She was also appointed the Inaugural Director of the Ginny L. Clements Breast Cancer Research Institute at University of Arizona Comprehensive Cancer Center, both in Tucson, AZ and holds the Ginny Clements Breast Cancer Clinical Endowed Chair. Before joining the University of Arizona Dr. Siziopikou served as Professor of Pathology and Medicine (Hematology & Oncology), and the Director of Breast Pathology at Northwestern University’s Feinberg School of Medicine and the Robert H. Lurie Comprehensive Cancer Center in Chicago, IL (2009-2025). Dr. Siziopikou established the first subspecialty Breast Pathology Section in The City of Chicago to support the multidisciplinary Breast Cancer Program at Northwestern and the Lurie Cancer Center. Dr. Siziopikou also established the Breast Pathology Fellowship Program at Northwestern and served as the Director of the fellowship from 2010-2022.

Dr. Siziopikou holds numerous national and international leadership roles. She serves in a number of capacities at the United States and Canadian Academy of Pathology (USCAP), the College of American Pathologists (CAP) and the International Society of Breast Pathology (ISBP) as well as on the Lynn Sage Breast Cancer Symposium scientific planning committee. She is an editorial board member for Breast Cancer Research and Treatment and section editor for breast pathology for the Archives of Pathology & Laboratory Medicine.

Dr. Siziopikou is a content expert for the sixth edition of the WHO Classification of Breast Tumors. She has held appointments with the American Association for Cancer Research (AACR), including service on its Pathology in Cancer Research Task Force and since 2022 on the Breast Cancer Research Grants Scientific Review Committee. Dr Siziopikou was a scientific committee member for the European Society for Medical Oncology (EMSO) 2024 and 2025 Congress. She also served on the Program Committee of the San Antonio Breast Cancer Symposium (SABCS) for multiple years and is the current Panel Chair for Pathology at SABCS. Her research area of excellence is translational breast cancer research where state-of-art scientific discovery drives impactful clinical decision making.

Residency

  • Beth Israel Hospital/Harvard Medical School, Boston, MA, Anatomic Pathology, 1990-1994

Degrees

  • MD: Aristotle's University School of Medicine, Thessaloniki, Greece, 1985
  • PhD: Immunology, Department of Immunology and Microbiology, Rush University, Chicago, IL, 1990

Fellowship

  • Beth Israel Hospital/Harvard Medical School Boston, MA, Breast Pathology, 1994-1995
  • Beth Israel Hospital/Harvard Medical School Boston, MA, Breast Cancer Research Fellowship, 1995-1997

Awards

  • 2025-present San Antonio Breast Cancer Symposium (SABCS) Program Planning Committee, Chairs Panel Member.
  • 2024-present WHO Classification of Breast Tumors Book (6th Edition), Expert/Consensus Faculty.
  • 2022-2025 European Society of Medical Oncology (ESMO) 2024 and 2025 Congress Scientific Committee Member.
  • 2022-present American Association for Cancer Research (AACR) Breast Cancer Research Grants Scientific Review Committee Member.
  • 2022-2025 American Association for Cancer Research (AACR) Pathology in Cancer Research Task Force Member.
  • 2022-present NRG Oncology Breast Cancer Core Committee Member.
  • 2021-2023 San Antonio Breast Cancer Symposium (SABCS) Program Planning Committee Member.
  • 2021-present Breast Cancer Research and Treatment, Editorial Advisory Board Member.
  • 2021-2024 United States and Canadian Academy of Pathology (USCAP) Abstract Assignment Committee Member, Lead Reviewer for Breast Pathology.
  • 2020-2021 San Antonio Breast Cancer Symposium (SABCS) Program Planning Committee Member.
  • 2019-present NRG Oncology Breast Committee Member.
  • 2019-2022 NRG Oncology Breast Committee Working Group Member
  • 2019-present NRG Oncology Translational Subcommittee Member.
  • 2019-present International Tumor Infiltrating Lymphocytes (TILs) Working Group Member.
  • 2019-2023 United States and Canadian Academy of Pathology (USCAP) Mentoring Academy Member, Mentor.
  • 2019-2021 American Journal of Surgical Pathology: Reviews and Reports, Editorial Board Member.
  • 2018-2021 United States and Canadian Academy of Pathology (USCAP) Abstract Review Board Member.
  • 2018-present NSABP Foundation Member.
  • 2017-2023 San Antonio Breast Cancer Symposium (SABCS) Program Planning Committee, Chairs Panel Member.
  • 2017-present College of American Pathologists (CAP) Abstract Review Committee, Member.
  • 2017 Northwestern University Feinberg School of Medicine. Outstanding Teacher Teaching Pin.
  • 2016-present Editorial Board of Archives of Pathology and Laboratory Medicine, Section Editor for Breast Pathology.
  • 2016-2020 International Society of Breast Pathology, Education and Meetings Secretary.
  • 2016-2018 San Antonio Breast Cancer Symposium (SABCS) Program Planning Committee Member.

Research Interests

Breast Cancer
Breast tumor markers of prognostic and predictive significance
Molecular diagnostics in breast cancer
Multidisciplinary breast cancer care
Artificial intelligence (AI) applications in Breast Pathology